SOLUTIONS FOR LIFE
Nikovari Bio Tech Oy is a biotechnology company established in Helsinki, Finland in 2017, backed with a combined experience and track record of 20 years in orthopaedics of the founding team. We are committed to delivering meaningful solutions in early intervention orthopedic care including osteoarthritis pain management and other joint preservation options to people suffering from degenerative joint pathology to relieve their pain and improve their quality of life.
INTRA-ARTICULAR INJECTIONS FOR A LONG TERM TREATMENT OF SYMPTOMATIC OSTEOARTHRITIS
PAIN RELIEF, RESTORED MOBILITY AND JOINT RECOVERY TO MEET ALL YOUR CLINICAL NEEDS
HYALURONIC ACID – A MULTITASKING MOLECULE
Provides anti-inflammatory, anabolic and chondroprotective actions, contributing to increase in viscosity and restored properties of synovial fluid.
BIOPORT® LINEAR 80
Is a sterile, biodegradable, isotonic, injectable gel, for intra-artcular use. BIOPORT® LINEAR 80 consists of medium chain (1.0-1.5 x 106 Dalton) hyaluronic acid, obtained from Streptococcus equi bacteria, formulated to a concentraton of 20 mg/ml in a physiologic bufer. The product, improving the characteristcs of the synovial fuid, exerts a protectve acton of the joints and helps the improvement of joint functon and the reducton of pain symptoms.


BIOPORT® LINEAR 80 /// PROPERTIES
Only one injection per treatment
Highly concentrated: 80 mg of linear hyaluronic acid per syringe
Delivered in pre-filled glass syringe Becton Dickinson
HYALURONIC ACID
Hyaluronic acid with a constant molecular weight between 1,200 and 1,500 kD allows optmal diffusion within the cartilage cell, reducing the risk of painful swelling of the injection site. Produced by Biofermentation of Streptococcus equi with no animal protein, it results in absolute purity, reducing the risk of allergens and inflammatory reactions to a minimum. Native hyaluronic acid (not chemically modified)
INDICATION
BIOPORT® LINEAR 80 is a synovial fuid substitute which, thanks to its viscoelastic and lubricant properties, promotes the restoration of rheological conditions of the joints, altered in degenerative or post-traumatic conditions. The product, improving the characteristics of the synovial fuid, exerts a protective action of the joints and helps the improvement of joint function and the reduction of pain symptoms.
EFFECTS
- Reduces pain
- Improves joint function and joint stiffness
- May postpone joint replacement
APPLICATION
A single injecton of the product restores the protection of the joint through good lubrication and shock absorption and leads to a significant improvement in symptoms.
OSTEOARTICULAR PATHOLOGIES AFFECT ABOUT 10% OF THE GLOBAL POPULATION.
Among these, osteoarthritis is one of the most frequent disorders, which is estimated to affect at least 57 million people in Europe alone.
BIOPORT® PLUS 1,5%
It replaces or reinforces the synovial fluid in the joints and is recommended for symptomatic treatment of synovial joint degeneration, including bone and joint inflammation.


BIOPORT® PLUS 1,5% /// PROPERTIES
Three injections per treatment
Highly purified 30mg hyaluronic acid per syringe
Highest degree of compatibility with properties of synovial fluid
Free from animal proteins
Delivered in pre-filled glass syringe Becton Dickinson
SODIUM HYALURONATE
In medical devices containing sodium hyaluronate for the viscoelastic supplementation of the synovial fluid, it is very important for the gel to imitate to the highest extent the synovial fluid and to be as close as possible to its properties, degrading as hard as possible in the joint.
INDICATION
- As a viscoelastic supplement or a replacement for synovial fluid in human knee joints
- For symptomatic treatment of knee osteoarthritis
EFFECTS
- Lubricant and mechanical support
- Improvement of joint mobility
APPLICATION
Depending on the degree of discomfort, about one injection per week, about 3 injections per treatment course. The effect can be sustained over a period of about 6 months.
BIOPORT PROVIDES PAIN RELIEF, LUBRICATION AND MECHANICAL SUPPORT.
BIOPORT is a sterile, viscoelastic solution for intra-articular injection.
BIOPORT® CROSSLINK 2%
It is a sterile viscoelastic solution for intra-articular injection, the two cross-linked biological polymers, sodium hyaluronate and chondroitin sodium sulfate involves.


BIOPORT® CROSSLINK 2% /// PROPERTIES
Only one injection per treatment
Highly concentrated: 60mg hyaluronic acid per syringe with chondroitin for cartilage tissue
Delivered in pre-filled glass syringe Becton Dickinson
CHONDROITIN SULFATE
Protects the cartilage and decreases inflammatory activity in the region affected by osteoarthritis (OA). Contributes to physical cross-linking of the hyaluronate chains being binded thereto in a 1:1 ration, increasing in this way the properties of sodium hyaluronate.
INDICATION
- As a viscoelastic supplement or as a replacement for the synovial fluid in the knee joint
- For the symptomatic treatment of mild to severe knee osteoarthritis
EFFECTS
- Pain relief
- Improvement of joint mobility
- Protection of the cartilage
APPLICATION
A single injection of the product restores the protection of the joint through good lubrication and shock absorption and leads to a significant improvement in symptoms.
PAIN RELIEF THAT TARGETS THE PAIN DIRECTLY
BIOPORT intra-articular injections are non-surgical alternatives in early intervention orthopedic care, aiming at providing safe, long-lasting pain relief.
BIOPORT® TRICOMBO
It is a biological matrix in the form of a sterile, viscoelastic solution containing Sodium hyaluronate and Chondroitin sodium surfate – two physically cross linked agents, highly purified polymers and N-acetylglucosamine(NAG),
a natural amino acid.


BIOPORT® TRICOMBO /// PROPERTIES
Only one injection per treatment
Highly concentrated: 36mg hyaluronic acid per syringe with chondroitin sodium sulfate, N-acetylglucosamine
Delivered in pre-filled glass syringe Becton Dickinson
N-ACETYLGLUCOSAMINE
Reduces cartilage degeneration and activates its regeneration processes. Glucosamine is an important precursor of glycoprotein and GAG synthesis
As for the cartilage, it is essential for the formation of hyaluronic acid, chondroitin sulfate, and keratin sulfate, which are – apart from collagen fibers – the most important components of the extracellular matrix of articular cartilage and synovial fluid.
INDICATION
- As a viscoelastic supplement or as a replacement for the synovial fluid in the knee joint
- For the symptomatic treatment of mild to severe knee osteoarthritis
EFFECTS
- Pain relief
- Lubrication and mechanical support
- Protection and regeneration of the cartilage
APPLICATION
A single injection of the product restores the protection of the joint through good lubrication and shock absorption and leads to a significant improvement in symptoms.
TO BE USED BY A PHYSICIAN ONLY
The injection of BIOPORT must be administered by authorized personnel depending on the needs of an individual patient and in accordance with local legislation.
BIOPORT® PLUS 1,5%
BIOPORT® CROSSLINK 2%
BIOPORT® LINEAR 80
BIOPORT® TRICOMBO
A WORLDWIDE PRESENCE
We believe in the power of collaboration, as partnerships achieve more.

BIOPORT Finland (HQ)
Life Science Center
Keilaranta 10 E, 02150 Espoo
+358 (0) 45214 8840
in**@*****rt.fi
BIOPORT FRANCE
3 rue du Premier de Ligne, 59400 CAMBRAI
+33 (0) 3 27 74 26 58
+33 (0) 6 44 28 0540
in**@*****rt.fr
SPAIN
INNOVACIONES EN ORTOPEDIA RENAC S.L.
Calle Ramon Cabanillas 16 bajo, 15679 Cambre – A Coruña
+34 619 975 275
re***@***ac.es
ITALY
SIFRA SRL
Via dello Stadio, 20
51100 Pistoia
+39 0573 1716561 int.1
in**@*******rl.it
TURKEY
Minerva Resources
Cumhuriyet Caddesi No: 65
Harbiye / Istanbul
in**@**************es.com
*also for distribution in MENA
BALTIC STATES
(Latvia, Lithuania, Estonia)
SIA NUEVO
Ogre, Skolas iela 18, Ogre, Ogres nov., LV5001, Latvija
+37 126 699 005
in**@***vo.lv
UNITED ARAB EMIRATES
OREX MEDICAL TRADING LLC
Office no 2 Al Basha Bldg-6 Al Warsan 4
P.O. Box 239249 Dubai
Mohamad Elhadi {Marketing Manager}
+971-4-2240567
in**@*********al.com
SOUTH AFRICA
Prime Surgical (Pty) Ltd
Unit A & B, 1 Avalon Road, Westlake View Ext 14,
Modderfontein,
Edenvale, South Africa
+27 11 531 5000
**@*************co.za
ARGENTINA
GRUPO ALEMANA
Avenida Vélez Sarsfield 55, Av. Vélez Sarsfield 55, C1282 Cdad.
Autónoma de Buenos Aires
www.grupoalemana.com
+54 114 409 5791
co*******@**********na.com
BECOME OUR PARTNER
We are looking to create a distribution partnerships worldwide and will be delighted to help you with any inquiry that you may have.
OSTEOARTHRITIS IS A LEADING CAUSE OF DISABILITY WORLDWIDE, LARGELY DUE TO ITS PRIMARY SYMPTOMS
BIOPORT injections are used to keep joints moving and reduce pain, especially when other treatments have not been effective or are unsuitable.